Cyanobacteria in general and marine forms in particular are one of the richest sources of known and novel bioactive compounds including toxins with wide pharmaceutical applications. The anti-inflammatory activity of marine cyanobacteria, Oscillatoria salina was studied in carrageenan - induced inflammation in rats. The ethanol extract of Oscillatoria salina showed anti- inflammatory activity at a high dosage (400 mg/kg) and this effect was on par with the commercial drug, indomethacin. The inhibition of inflammation volume was 65.8? 0.4 % and 48.7?0.4 % respectively at higher and lower dosages, in 30 minutes of treatment. The control group without any treatment exhibited an increase in the paw volume. The results indicate, further isolation of the anti-inflammatory molecules will be derived from Oscillatoria salina.
Loading....